Our Publications

Norris T, Cooper R, Garfield V, Hamer M, Pinto Pereira SM. Unpicking Causal Relationships Between Grip Strength and Cardiorespiratory Fitness: A Bidirectional Mendelian Randomization Study. Scandinavian Journal of Medicine & Science in Sports. 2024 Dec;34(12):e14775

Suetterlin K, Law S, Arnold WD Periodic paralysis across the life course: age-related phenotype transition and sarcopenia overlap. Frontiers in Neurology. 2024 Dec 23:15:1507485

Prowse J, Jaiswal S, Gentle J, Sorial AK, Witham MD.Feasibility, acceptability and prognostic value of muscle mass and strength measurement in patients with hip fracture: a systematic review. European Geriatric Medicine. 2024 Dec;15(6):1603-1614

Granic A, Cooper R, Hurst C, Hillman SJ, Dodds RM, Witham MD, Sayer AA. Cross-sectional and longitudinal associations between glycaemic measures and grip strength in people without diabetes in the UK Biobank cohort study. European Geriatric Medicine. 2024 Nov 29

Berg K, Dockrell D, Colvin L, Fraser WD, Tang JC, Aspray T, Dennison E, Divyateja H, Ghouri N, Hanison E, Keen R, McCloskey E, O'Neill TW, Rahman F, Siddiqi M, Tuck S, Turton J, Ralston SH. Causes of Musculoskeletal Pain in Paget's Disease of Bone. Calcified Tissue International. 2024 Nov;115(5):533-541

Wunnava SSJ, Ravulapalli K, El-Sayed T, Sivaharan A, Sillito S, Witham M, Nandhra S. Impact of Age Differences in Chronic Limb Threatening Ischaemia Outcomes in Octogenarians. Annals of Vascular Surgery. 2024 Nov 23:111:212-224

Treweek S, Gillies K, Witham MD, Devane D, Khunti K, Bower P, Parker A, Soulsby I, Ostrovska B, Prowse S, Green H. How should trial teams make decisions about the proportions and diversity of the ethnic groups in their trial? Trials. 2024 Nov 15;25(1):768

Shield A, Romano V, Robinson SM, Witham MD. Describing Community-Based Nurses' Knowledge, Attitudes, and Practices in the Nutritional Care of Older Adults: Results of a UK Survey. Journal of Gerontological Nursing. 2024 Nov;50(11):13-19

Sun Y, Witham MD, Clegg A, Taylor RS, Dibben G, McAllister D, Hanlon P. A scoping review of the measurement and analysis of frailty in randomised controlled trials. Age and Ageing. 2024 Nov 1;53(11):afae258

Payne L, Grey E, Sutcliffe M, Green S, Childs C, Robinson S, Gudgin B, Holloway P, Kelly J, Seely J, Le Feuvre R, Aveyard P, Gill P, Stroud M, Little P, Lucy Y, Morrison L What helps or hinders intervention success in primary care? Qualitative findings with older adults and primary care practitioners during a feasibility study to address malnutrition risk 2024 Oct 23. BMC Primary Care 25, 377 (2024)

Dismore L, Taylor L, Hurst C, Aujayeb A, Poulter H, & Swainston K Experiences of Physical Activity in Mesothelioma: A Qualitative Enquiry Journal of Respiration 2024 Oct 16, 4(4), 188-197

Hurst C, Dismore L, Granic A, Noble JM, Hillman SJ, Witham MD, Sayer AA, Dodds RM, Robinson SM. The feasibility and acceptability of engaging older adults living with multiple long-term conditions, frailty, and a recent deterioration in health in research: Findings from the Lifestyle in Later Life - Older People's Medicine (LiLL-OPM) study. BMC Geriatrics 2024 Oct 14;24(1):831

Renji R, Robinson SM, Witham MD Effects of Dietary Nitrate Supplementation on Physical Performance and Muscle Strength in Older People—A Systematic Review JCSM Communications 2024 Oct 4;7(2):143-156

McDonald C, Sayer AA, Witham MD. Geriatric medicine and Olympic elite sports-parallels and philosophies. Age and Ageing. 2024 Oct 1;53(10):afae212

Sayer AA, Cooper R, Arai H, Cawthon PM, Ntsama Essomba MJ, Fielding RA, Grounds MD, Witham MD, Cruz-Jentoft AJ. Sarcopenia. Nature Reviews Disease Primers. 2024 Sep 19;10(1):68

Hayes EJ, Hurst C, Granic A, Sayer AA, Stevenson E. Challenges in Conducting Exercise Recovery Studies in Older Adults and Considerations for Future Research: Findings from a Nutritional Intervention Study. Geriatrics (Basel). 2024 Sep 10;9(5):116

Hillman SJ, Dodds RM, Granic A, Witham MD, Sayer AA, Cooper R.Identifying combinations of long-term conditions associated with sarcopenia: a cross-sectional decision tree analysis in the UK Biobank study. BMJ Open. 2024 Sep 5;14(9):e085204

Caulfield L, Arnold S, Biase S, Buckland C, Heslop P, Hurst C, Sayer AA, Skelton DA, Witham MD. The Benchmarking Exercise Programme for Older People (BEPOP): Design, Results and Recommendations from The First Wave of Data Collection. Journal of Frailty, Sarcopenia and Falls. 2024 Sep 1;9(3):169-183

Krauth S J, Steell L,  Ahmed S, McIntosh E, Dibben G O, Hanlon P, Lewsey J, Nicholl B I, McAllister D A, Smith S M, Evans R, Ahmed Z, Dean S, Greaves C, Barber S, Doherty P, Gardiner N, Ibbotson T, Jolly K, Ormandy P, Jani B D Association of latent class analysis-derived multimorbidity clusters with adverse health outcomes in patients with multiple long-term conditions: comparative results across three UK cohorts EClinicalMedicine 2024 Aug;74: 102703

Blair C, Shields J, Mullan R, Johnston W, Davenport A, Fouque D, Kalantar-Zadeh K, Maxwell P, McKeaveney C, Noble H, Porter S, Seres D, Slee A, Swaine I, Witham M, Reid J. The lived experience of renal cachexia: An interpretive phenomenological analysis. International Journal of Nursing Studies Advances. 2024 Aug 22:7:100235

Shrestha A, Bashir T, Achison M, Adamson S, Akpan A, Aspray T, Avenell A, Band MM, Burton LA, Cvoro V, Donnan PT, Duncan GW, George J, Gordon AL, Gregson CL, Hapca A, Hume C, Jackson TA, Kerr S, Kilgour A, Masud T, McKenzie A, McKenzie E, Patel H, Pilvinyte K, Roberts HC, Sayer AA, Rossios C, Smith KT, Soiza RL, Steves CJ, Struthers AD, Tiwari D, Whitney J, Witham MD, Kemp PR. Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: Findings from the LACE sarcopenia trial. PLoS One. 2024 Aug 2;19(8):e0307268

Suetterlin K, Mӓnnikkӧ R, Jayaseelan DL. Inherited myotonias. Handbook of Clinical Neurology. 2024 Aug 1:203:25-38

Kirk B, Cawthon PM, Arai H, Ávila-Funes JA, Barazzoni R, Bhasin S, Binder EF, Bruyère O, Cederholm T, Chen LK, Cooper C, Duque G, Fielding RA, Guralnik J, Kiel DP, Landi F, Reginster JY, Sayer AA, Visser M, von Haehling S, Woo J, Cruz-Jentoft AJ; Global Leadership Initiative in Sarcopenia (GLIS) Group. An executive summary on the Global conceptual definition of Sarcopenia. Aging Clinical and Experimental Research. 2024. Jul 27;36(1):153

Blodgett JM, Bann D, Chastin SFM, Ahmadi M, Stamatakis E, Cooper R, Hamer M. Socioeconomic gradients in 24-hour movement patterns across weekends and weekdays in a working-age sample: evidence from the 1970 British Cohort Study. Journal of Epidemiology and Community Health. 2024 Jul 10;78(8):515-521

Osman M, Cooper R, Sayer AA, Witham MD.The use of natural language processing for the identification of ageing syndromes including sarcopenia, frailty and falls in electronic healthcare records: a systematic review. Age and Ageing. 2024 Jul 2;53(7):afae135

Goodman-Palmer D, Greig C, Agyapong-Badu S, Witham MD, Payne CF, Bountogo M, Coulibaly B, Geldsetzer P, Harling G, Inghels M, Manne-Goehler J, Ouermi L, Sie A, Davies JI. Frailty progression in adults aged 40 years and older in rural Burkina Faso: a longitudinal, population-based study. The Lancet Healthy Longevity. 2024 Jul;5(7):e493-e502

Richardson SJ, Cropp AD, Ellis SW, Gibbon J, Sayer AA, Witham MD. The interrelationship between multiple long-term conditions (MLTC) and delirium: a scoping review. Age and Ageing. 2024 Jul 2;53(7):afae120

Cooper R, Bunn JG, Richardson SJ, Hillman SJ, Sayer AA, Witham MD; ADMISSION research collaborative. Rising to the challenge of defining and operationalising multimorbidity in a UK hospital setting: the ADMISSION research collaborative. European Geriatric Medicine. 2024 Jun;15(3):853-860

Dismore L, Taylor L, Aujayeb A, Hurst C, Swainston K. Patients with mesothelioma and their carer's experience of diet and appetite: A qualitative insight from the Help-Meso Study. Journal of Human Nutrition and Dietetics. 2024 Jun;37(3):717-725

Bowler C, Moriarty E, Chawner M, Clegg A, Biase S, Offord N, Romano V, Sayer AA, Smith A, Todd O, Witham MD. Nutritional Screening, Initial Management and Referral for Older People with Sarcopenia or Frailty - Results from a UK-Wide Survey. Journal of Frailty, Sarcopenia and Falls. 2024 Jun 1;9(2):131-141

Taylor L, Swainston K, Hurst C, Aujayeb A, Dismore L Nutritional management in mesothelioma: Qualitative insights into healthcare professionals’ perceptions and experiences. Cancer Nursing Practice. 2024 Jun

Montgomery G, Yusuf M, Cooper R, Ireland A. Are associations between physical activity and bone mineral density in adults sex- and age-dependent? An analysis of the UK biobank study. Journal of Bone and Mineral Research. 2024 May 2;39(4):399-407

Granic A, Cooper R, Robinson SM, Sayer AA. Myoprotective whole foods, muscle health and sarcopenia in older adults. Current Opinion in Clinical Nutrition and Metabolic Care. 2024 May 1;27(3):244-251

Dibben G O, Gardiner L, Young M H L, Wells V, Evans R A, Ahmed Z, Barber S, Dean S, Doherty P, Gardiner N, Greaves C,  Ibbotson T, Jani B D, Jolly K, Mair F S, McIntosh E,  Ormandy P,  Simpson S A, Ahmed S, Krauth S J,  Steell L, Singh S J, Taylor R S,  Begum S,  DeBarros C,  Davies F, Sterniczuk K,  Kumar R,  Longley R,  Freeman A,  Lalseta J, Ashby P, Grieken M V, Elder D G Evidence for exercise-based interventions across 45 different long-term conditions: an overview of systematic reviews EClinicalMedicine. 2024 Apr 30:72:102599

Staines KA, Saunders FR, Ireland A, Aspden RM, Gregory JS, Hardy RJ, Cooper R.Associations between life course longitudinal growth and hip shapes at ages 60-64 years: evidence from the MRC National Survey of Health and Development. RMD Open. 2024 Apr 10;10(2):e003816

Flores-Flores O, Zevallos-Morales A, Pollard SL, Checkley W, Siddharthan T, Hurst JR, Bernabé-Ortiz A, Runzer-Colmenares FM, Witham MD, Parodi JF. Sarcopenia and sarcopenic obesity among community-dwelling Peruvian adults: A cross-sectional study. PLoS One. 2024 Apr 9;19(4):e0300224

Kirk B, Cawthon PM, Arai H, Ávila-Funes JA, Barazzoni R, Bhasin S, Binder EF, Bruyere O, Cederholm T, Chen LK, Cooper C, Duque G, Fielding RA, Guralnik J, Kiel DP, Landi F, Reginster JY, Sayer AA, Visser M, von Haehling S, Woo J, Cruz-Jentoft AJ; Global Leadership Initiative in Sarcopenia (GLIS) group. The Conceptual Definition of Sarcopenia: Delphi Consensus from the Global Leadership Initiative in Sarcopenia (GLIS). Age and Ageing. 2024 Mar 1;53(3):afae052

McDonald C, Cooper R, Sayer AA, Witham MD.Improving care for patients with multiple long-term conditions admitted to hospital: challenges and potential solutions. British Journal of Hospital Medicine. 2024 Mar 2;85(3):1-8

Gerakios F, Yarnall AJ, Bate G, Wright L, Davis D, Stephan BCM, Robinson L, Brayne C, Stebbins G, Taylor JP, Burn DJ, Allan LM, Richardson SJ, Lawson RA. Delirium is more common and associated with worse outcomes in Parkinson's disease compared to older adult controls: results of two prospective longitudinal cohort studies. Age and Ageing. 2024 Mar 1;53(3):afae046

McDonald C, Alderson C, Birkbeck MG, Brown L, Del Din S, Gorman GG, Hollingsworth K, Massarella C, Rehman R, Rochester L, Sayer AA, Su H, Tuppen H, Warren C, Witham MD.A study protocol to investigate if acipimox improves muscle function and sarcopenia: an open-label, uncontrolled, before-and-after experimental medicine feasibility study in community-dwelling older adults. BMJ Open. 2024 Feb 27;14(2):e076518

Lewis J, Evison F, Doal R, Field J, Gallier S, Harris S, le Roux P, Osman M, Plummer C, Sapey E, Singer M, Sayer AA, Witham MD; ADMISSION Research Collaborative. How far back do we need to look to capture diagnoses in electronic health records? A retrospective observational study of hospital electronic health record data. BMJ Open. 2024 Feb 13;14(2):e080678

Rimmer L, Mann DA, Sayer AA, Amarnath S, Granic A. A silver bullet for ageing medicine?: clinical relevance of T-cell checkpoint receptors in normal human ageing. Frontiers in Immunology. 2024 Feb 1;15:1360141

Dismore L, Sayer A, Robinson S. Exploring the experience of appetite loss in older age: insights from a qualitative study. BMC Geriatrics. 2024 Jan 31;24(1):117

Bellass S, Scharf T, Errington L, Bowden Davies K, Robinson S, Runacres A, Ventre J, Witham MD, Sayer AA, Cooper R. Experiences of hospital care for people with multiple long-term conditions: a scoping review of qualitative research. BMC Medicine. 2024 January 17;22(1):25

Lessof C, Cooper R, Wong A, Bendayan R, Caleyachetty R, Cheshire H, Cosco T, Elhakeem A, Hansell AL, Kaushal A, Kuh D, Martin D, Minelli C, Muthuri S, Popham M, Shaheen SO, Sturgis P, Hardy R. Comparison of devices used to measure blood pressure, grip strength and lung function: A randomised cross-over study. PLoS One. 2023 Dec 27;18(12):e0289052

Osman M, Witham MD, Sayer AA, Cooper R. Optimising the use of SARC-F for the identification of muscle weakness by considering alternative cut-points: findings from the Newcastle SarcScreen project. European Geriatric Medicine. 2023 Dec;14(6):1327-1331.

Dismore L, Hurst C, Granic A, Tullo E, Witham MD, Dodds RM, Sayer AA, Robinson SM. Why are older adults living with the complexity of multiple long-term conditions, frailty and a recent deterioration in health under-served by research? A narrative synthesis review of the literature. Journal of Frailty, Sarcopenia and Falls. 2023 Dec 1;8(4):230-239

Granic A, Suetterlin K, Shavlakadze T, Grounds MD, Sayer AA. Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men. Clinical Science. 2023 Nov 29;137(22):1721-1751

Hurst C, Dismore L, Granic A, Tullo E, Noble JM, Hillman SJ, Witham MD, Sayer AA, Dodds RM, Robinson SM. Attitudes and barriers to resistance exercise training for older adults living with multiple long-term conditions, frailty, and a recent deterioration in health: qualitative findings from the Lifestyle in Later Life - Older People's Medicine (LiLL-OPM) study. BMC Geriatrics. 2023 Nov 24;23(1):772

Johansson J, Grimsgaard S, Strand BH, Sayer AA, Cooper R. Comparing associations of handgrip strength and chair stand performance with all-cause mortality-implications for defining probable sarcopenia: the Tromsø Study 2015-2020. BMC Medicine. 2023 Nov 20;21(1):451

Bashir T, Achison M, Adamson S, Akpan A, Aspray T, Avenell A, Band MM, Burton LA, Cvoro V, Donnan PT, Duncan GW, George J, Gordon AL, Gregson CL, Hapca A, Hume C, Jackson TA, Kerr S, Kilgour A, Masud T, McKenzie A, McKenzie E, Patel H, Pilvinyte K, Roberts HC, Rossios C, Sayer AA, Smith KT, Soiza RL, Steves CJ, Struthers AD, Tiwari D, Whitney J, Witham MD, Kemp PR. Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia-Analyses from the LACE randomised controlled trial. PLoS One. 2023 Nov 14;18(11)

Robinson S, Granic A, Cruz-Jentoft AJ, Sayer AA. The role of nutrition in the prevention of sarcopenia. The American Journal of Clinical Nutrition. 2023 Nov;118(5):852-864

Witham MD, Bridges J, Gladman J, Gordon AL, Kay S, Manthorpe J, Roberts HC, Rochester L, Todd O, Usman A, Sayer AA. Spotlight on the academic multidisciplinary team: proposals from the 3rd NIHR Newcastle BRC Academic Geriatric Medicine Workshop. Clinical Medicine. 2023 Nov;23(6):611-614

Farquhar R, Matthews S, Baxter N, Rayers G, Ratnayake CBB, Robertson FP, Nandhra S, Lim WB, Witham M, Pandanaboyana S. Sarcopenia and Sarcopenic Obesity on Body Composition Analysis is a Significant Predictor of Mortality in Severe Acute Pancreatitis: A Longitudinal Observational Study. World Journal of Surgery. 2023 Nov;47(11):2825-2833.

Rossios C, Bashir T, Achison M, Adamson S, Akpan A, Aspray T, Avenell A, Band MM, Burton LA, Cvoro V, Donnan PT, Duncan GW, George J, Gordon AL, Gregson CL, Hapca A, Hume C, Jackson TA, Kerr S, Kilgour A, Masud T, McKenzie A, McKenzie E, Patel H, Pilvinyte K, Roberts HC, Sayer AA, Smith KT, Soiza RL, Steves CJ, Struthers AD, Tiwari D, Whitney J, Witham MD, Kemp PR. ACE I/D genotype associates with strength in sarcopenic men but not with response to ACE inhibitor therapy in older adults with sarcopenia: Results from the LACE trial. PLoS One. 2023 Oct 20;18(10):e0292402

Evison F, Cooper R, Gallier S, Missier P, Sayer AA, Sapey E, Witham MD. Mapping inpatient care pathways for patients with COPD: an observational study using routinely collected electronic hospital record data. ERJ Open Research. 2023 Oct 16;9(5):00110-2023

Norris T, Sanderson E, Cooper R, Garfield V, Pereira SMP. Chronic inflammation does not mediate the effect of adiposity on grip strength: results from a multivariable Mendelian randomization study. Scientific Reports. 2023 Oct 6;13(1):16886

Graham L, Armitage J, Vitorio R, Das J, Barry G, Godfrey A, McDonald C, Walker R, Mancini M, Morris R, Stuart S. Visual Exploration While Walking With and Without Visual Cues in Parkinson's Disease: Freezer Versus Non-Freezer. Neurorehabil Neural Repair 2023 Oct;37(10):734-743.

Birkbeck MG, Heskamp L, Schofield IS, Hall J, Sayer AA, Whittaker RG, Blamire AM. Whole Muscle and Single Motor Unit Twitch Profiles in a Healthy Adult Cohort Assessed With Phase Contrast Motor Unit MRI (PC-MUMRI). Journal of Magnetic Resonance Imaging. 2024 Jul;60(1):205-217. Epub 2023 Sep 30.

Allan L, O'Connell A, Raghuraman S, Bingham A, Laverick A, Chandler K, Connors J, Jones B, Um J, Morgan-Trimmer S, Harwood R, Goodwin VA, Ukoumunne OC, Hawton A, Anderson R, Jackson T, MacLullich AMJ, Richardson S, Davis D, Collier L, Strain WD, Litherland R, Glasby J, Clare L. A rehabilitation intervention to improve recovery after an episode of delirium in adults over 65 years (RecoverED): study protocol for a multi-centre, single-arm feasibility study. Pilot and Feasability Studies. 2023 Sep 15;9(1):162

Wylie G, Kroll T, Witham MD, Morris JWylie G, Kroll T, Morris J. Increasing physical activity levels in care homes for older people: a quantitative scoping review of intervention studies to guide future research. Disability and Rehabilitation. 2023 Sep;45(19):3160-3176

Graham L, Das J, Vitorio R, McDonald C, Walker R, Godfrey A, Morris R, Stuart S. Ocular microtremor: a structured review. Experimental Brain Research. 2023 Sep;241(9):2191-2203

Witham MD, Cooper R, Missier P, Robinson SM, Sapey E, Sayer AA. Researching multimorbidity in hospital: can we deliver on the promise of health informatics? European Geriatric Medicine. 2023 Aug;14(4):765-768

Hart A, Cordova-Rivera L, Barker F, Sayer AA, Granic A, Yarnall AJ. The prevalence of sarcopenia in Parkinson's disease and related disorders- a systematic review. Neurological Sciences. 2023 Aug 18;44:4205–4217

Scott S, Atkins B, Martin-Kerry JM, Pritchard M, Alldred DP, Clark AB, Colles A, Hammond A, Murphy K, Keevil VL, Kellar I, Patel M, Sims E, Taylor J, Turner D, Witham M, Wright D, Bhattacharya D. CompreHensive geriAtRician-led MEdication Review (CHARMER): protocol for a feasibility study of a hospital deprescribing behaviour change intervention. BMJ Open. 2023 Aug 4;13(8):e075795

Pinto Pereira SM, Garfield V, Norris T, Burgess S, Williams DM, Dodds R, Sayer AA, Robinson SM, Cooper R.Linear and Nonlinear Associations Between Vitamin D and Grip Strength: A Mendelian Randomization Study in UK Biobank. The Journals of Gerontology 2023 Aug 2;78(8):1483-1488

Witham MD, Granic A, Pearson E, Robinson SM, Sayer AA. Repurposing Drugs for Diabetes Mellitus as Potential Pharmacological Treatments for Sarcopenia - A Narrative Review. Drugs & Aging. 2023 Aug;40(8):703-719

Whitehead LE, Sailer O, Witham MD, Wason JMS Bayesian borrowing for basket trials with longitudinal outcomes. Statistics in Medicine. 2023 Jul 20;42(16):2819-2840

Habiballa L, Hruby A, Granic A, Dodds RM, Hillman SJ, Jurk D, Passos JF, Sayer AA. Determining the feasibility of characterising cellular senescence in human skeletal muscle and exploring associations with muscle morphology and physical function at different ages: findings from the MASS_Lifecourse Study. Geroscience. 2023 Jul 11

Hayes EJ, Stevenson E, Sayer AA, Granic A, Hurst C. Recovery from Resistance Exercise in Older Adults: A Systematic Scoping Review. Sports Medicine Open. 2023 Jul 3;9(1):51

Witham MD, Granic A, Miwa S, Passos JF, Richardson GD, Sayer AA. New Horizons in cellular senescence for clinicians. Age and Ageing. 2023 Jul 1;52(7):afad127

Hurst C, Dismore L, Granic A, Tullo E, Noble JM, Hillman SJ, Witham MD, Sayer AA, Dodds RM, Robinson SM. Feasibility of engaging older adults living with multiple long-term conditions, frailty, and a recent deterioration in health in a study of lifestyle: protocol for the LiLL-OPM study. Journal of Frailty, Sarcopenia and Falls. 2023 Jun 1;8(2):127-135

Goodwin VA, Low MSA, Quinn TJ, Cockcroft EJ, Shepherd V, Evans PH, Henderson EJ, Mahmood F, Ni Lochlainn M, Needham C, Underwood BR, Arora A, Witham MD. Including older people in health and social care research: best practice recommendations based on the INCLUDE framework. Age and Ageing. 2023 Jun 1;52(6):afad082

Scott S, Atkins B, Kellar I, Taylor J, Keevil V, Alldred DP, Murphy K, Patel M, Witham MD, Wright D, Bhattacharya D. Co-design of a behaviour change intervention to equip geriatricians and pharmacists to proactively deprescribe medicines that are no longer needed or are risky to continue in hospital Research in Social and Administrative Pharmacy. 2023 May:S1551-7411(23)00060-8

Tsui A, Yeo N, Searle SD, Bowden H, Hoffmann K, Hornby J, Goslett A, Weston-Clarke M, Lanham D, Hogan P, Seeley A, Rawle M, Chaturvedi N, Sampson EL, Rockwood K, Cunningham C, Ely EW, Richardson SJ, Brayne C, Muniz Terrera G, Tieges Z, MacLullich AMJ, Davis D Extremes of baseline cognitive function determine the severity of delirium: a population study. Brain. 2023 May 2;146(5):2132-2141

Stubbs TA, Doherty WJ, Chaplin A, Langford S, Reed MR, Sayer AA, Witham MD, Sorial AK. Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture. European Geriatric Medicine. 2023 Apr;14(2):285-293

Bennett JL, Egail M, Anderson AE, Dodds R, Feeney C, Gorman GS, Pratt AG, Sayer AA, Hollingsworth JG, Isaacs JD. The Rheumatoid Arthritis and MUScle (RAMUS) Study: Protocol for an observational single-arm study of skeletal muscle in patients with rheumatoid arthritis receiving tofacitinib Journal of Frailty, Sarcopenia and Falls. 2023 Mar 1;8(1):53-59

McKeaveney C, Witham M, Alamrani AO, Maxwell AP, Mullan R, Noble H, Shields J, Reid J. Quality of life in advanced renal disease managed either by haemodialysis or conservative care in older patients BMJ Supportive & Palliative Care BMJ Support Palliat Care. 2023 Mar;13(1):87-9

Welch C, Wilson D, Sayer AA, Witham MD, Jackson TA; UK Geriatric Medicine Core Dataset Extended Working Group Development of a UK core dataset for geriatric medicine research: a position statement and results from a Delphi consensus process. BMC Geriatrics. 2023 Mar 23;23(1):168

Bennett JL, Pratt AG, Dodds R, Sayer AA, Isaacs JD. Rheumatoid sarcopenia: Loss of skeletal muscle strength and mass in rheumatoid arthritis. Nature Reviews Rheumatology. 2023 Feb 17;19(4):239-251

Marsland I, Sobala R, De Soyza A, Witham M. Multimorbidity in bronchiectasis: a systematic scoping review ERJ Open Research. 2023 Jan 16;9(1):00296-2022

Adamson A, Davies K, Wham C, Kepa M, Foster E, Jones A, Mathers J, Granic A, Teh R, Moyes S, Hayman K, Siervo M, Maxted E, Redwood K, Collerton J, Jagger C, Kirkwood T, Dyall L, Kerse N. Assessment of Dietary Intake in Three Cohorts of Advanced Age in Two Countries: Methodology Challenges The Journal of Nutrition, Health & Aging. 2023 Jan 9;27(1):59-66

Blodgett JM, Hardy R, Davis DHJ, Peeters G, Hamer M, Kuh D, Cooper R. Prognostic accuracy of the one-legged balance test in predicting falls:15-years of midlife follow-up in a British birth cohort study Frontiers in Sports and Active Living. 2023 Jan 9;4:1066913

Dodds RM, Bunn JG, Hillman SJ, Granic A, Murray J, Witham MD, Robinson SM, Cooper R, Sayer AA. Simple approaches to characterising multiple long-term conditions (multimorbidity) and rates of emergency hospital admission: Findings from 495,465 UK Biobank participants. Journal of Internal Medicine. 2023 Jan;293(1):100-109

Heslop PA, Hurst C, Sayer AA, Witham MDRemote collection of physical performance measures for older people: a systematic review. Age and Ageing. 2023 Jan;52(1):afac327

Pinto Pereira SM, Garfield V, Norris T, Burgess S, Williams DM, Dodds R, Sayer AA, Robinson SM, Cooper RLinear and Non-linear associations between vitamin D and grip strength: a Mendelian Randomisation study in UK Biobank The Journals of Gerontology Series A Biological Sciences and Medical Sciences 2022 Dec 25;78(8):1483-1488

Granic A, Martin-Ruiz C, Rimmer L, Dodds RM, Robinson LA, Spyridopoulos I, Kirkwood TB, von Zglinicki T, Sayer AA. Immunosenescence profiles of lymphocyte compartments and multiple long-term conditions (multimorbidity) in very old adults: The Newcastle 85+ Study. Mechanisms of Ageing and Development 2022 Dec; 208:111739

Witkam R, Verstappen SMM, Gwinnutt JM, Cook MJ, O'Neill TW, Cooper R, Humphreys J. The association between lower socioeconomic position and functional limitations is partially mediated by obesity in older adults with symptomatic knee osteoarthritis: Findings from the English Longitudinal Study of Ageing. Frontiers in Public Health. 2022 Dec;10:1053304.

Cox NJ, Howson F, Ibrahim K, Morrison L, Sayer AA, Roberts HC, Robinson SMMood and physical activity are associated with appetite in hospitalised older men and women. Age and Ageing. 2022 Dec;51(12):afac297

Cawthon PM, Visser M, Arai H, Ávila-Funes JA, Barazzoni R, Bhasin S, Binder E, Bruyère O, Cederholm T, Chen LK, Cooper C, Duque G, Fielding RA, Guralnik J, Kiel DP, Kirk B, Landi F, Sayer AA, Von Haehling S, Woo J, Cruz-Jentoft AJ. Defining terms commonly used in sarcopenia research: a glossary proposed by the Global Leadership in Sarcopenia (GLIS) Steering Committee. European Geriatric Medicine. 2022 Nov 29;3:1239–1244

Blair C, Slee A, Davenport A, Fouque D, Johnston W, Kalantar-Zadeh K, Maxwell P, McKeaveney C, Mullan R, Noble H, Porter S, Seres D, Shields J, Swaine I, Witham M, Reid J. Developing an Evidence and Theory Based Multimodal Integrative Intervention for the Management of Renal Cachexia: A Theory of Change. Healthcare (Basel). 2022 Nov 22;10(12):2344

Blodgett JM, Hardy R, Davis D, Peeters G, Kuh D, Cooper R. One-Legged Balance Performance and Fall Risk in Mid and Later Life: Longitudinal Evidence From a British Birth Cohort. American Journal of Preventative Medicine. 2022 Nov 17;63(6):997-1006

Blair C, Shields J, Mullan R, Johnston W, Davenport A, Fouque D, Kalantar-Zadeh K, Maxwell P, McKeaveney C, Noble H, Porter S, Seres D, Slee A, Swaine I, Witham M, Reid J. Exploring the lived experience of renal cachexia for individuals with end-stage renal disease and the interrelated experience of their carers: Study protocol. PLoS One. 2022 Nov 3;17(11):e0277241

Martin-Kerry J, Taylor J, Scott S, Patel M, Wright D, Clark A, Turner D, Alldred DP, Murphy K, Keevil V, Witham MD, Kellar I, Bhattacharya D. Developing a core outcome set for hospital deprescribing trials for older people under the care of a geriatrician. Age Ageing. 2022 Nov;51(11):afac241

Sayer AA, Cruz-Jentoft A. Sarcopenia definition, diagnosis and treatment: consensus is growing. Age and Ageing. 2022 Oct 24;51(10);afac220

Lewis EG, Gray WK, Walker R, Urasa S, Witham M, Dotchin C. Multimorbidity and its socio-economic associations in community-dwelling older adults in rural Tanzania; a cross-sectional study. BMC Public Health. 2022 Oct 22;22(1):1918

Richardson S, Lawson RA, Price A, Taylor JP. Challenges in diagnosis and management of delirium in Lewy body disease. Acta Psychiatrica Scandinavica. 2022 Oct 25

Witkam R, Gwinnutt JM, Selby DA, Cooper R, Humphreys JH, Verstappen SM. Does body mass index mediate the relationship between socioeconomic position and incident osteoarthritis? Seminars in Arthritis and Rheumatism. 2022 Oct; 56:152063

Witham MD, Cooper R, Bowden Davies KA, Ortega-Martorell S, Stewart CE, Sayer AA. Ageing Research Translation: a new era for UK geroscience. Nature Aging. 2022 Sep 26;2(10):867-868

Essery R, Pollet S, Bradbury K, Western MJ, Grey E, Denison-Day J, Smith KA, Hayter V, Kelly J, Somerville J, Stuart B, Becque T, Zhang J, Slodkowska-Barabasz J, Mowbray F, Ferrey A, Yao G, Zhu S, Kendrick T, Griffin S, Mutrie N, Robinson S, Brooker H, Griffiths G, Robinson L, Rossor M, Ballard C, Gallacher J, Rathod S, Gudgin B, Phillips R, Stokes T, Niven J, Little P, Yardley L. Parallel randomized controlled feasibility trials of the "Active Brains" digital intervention to protect cognitive health in adults aged 60-85. Frontiers in Public Health. 2022 Sep 20;10:962873

Wylie G, Kroll T, Witham MD, Morris J. Increasing physical activity levels in care homes for older people: a quantitative scoping review of intervention studies to guide future research. Disability and Rehabilitation. 2023 Sep;45(19):3160-3176. Epub 2022 Sep 10

Dawson S, Banister K, Biggs K, Cotton S, Devane D, Gardner H, Gillies K, Gopalakrishnan G, Isaacs T, Khunti K, Nichol A, Parker A, Russell AM, Shepherd V, Shiely F, Shorter G, Starling B, Williams H, Willis A, Witham MD, Treweek S. Correction: Trial Forge Guidance 3: randomised trials and how to recruit and retain individuals from ethnic minority groups-practical guidance to support better practice. Trials. 2022 Sep 7; 23:760

Dodds RM, Hurst C, Hillman SJ, Davies K, Roberts L, Aspray TJ, Granic A, Sayer AA. Advancing our understanding of skeletal muscle across the lifecourse: Protocol for the MASS_Lifecourse study and characteristics of the first 80 participants. Experimental Gerontology. 2022 Sep; 166:111884

Odland ML, Gassama K, Bockarie T, Wurie H, Ansumana R, Witham MD, Oyebode O, Hirschhorn LR, Davies JI. Cardiovascular disease risk profile and management among people 40 years of age and above in Bo, Sierra Leone: A cross-sectional study. PLoS One. 2022 Sep 9;17(9):e0274242

Blodgett JM, Cooper R, Pinto Pereira SM, Hamer M. Stability of Balance Performance From Childhood to Midlife. Pediatrics. 2022 July; 150(1):e2021055861

Cooper R, Witham MD, Bartle V and Sayer AA. Defining and measuring multiple long-term conditions in research.  BMJ Medicine 2022 Jul 27; 1:e000287

Gibbon JR, Parry SW, Witham MD, Yarnall A, Frith J. Feasibility, reliability and safety of self-assessed orthostatic blood pressure at home. Age and Ageing. 2022 Jul;51(7):afac153

Yusuf M, Montgomery G, Hamer M, McPhee J and Cooper R. Associations between childhood and adulthood socioeconomic position and grip strength at age 46 years: findings from the 1970 British Cohort Study. BMC Public Health. 2022 Jul 27; 22(1):1427

Rennie KJ, Witham M, Bradley P, Clegg A, Connolly S, Hancock HC, Hiu S, Marsay L, McDonald C, Robertson L, Simms L, Steel AJ, Steves CJ, Storey B, Wason J, Wilson N, von Zglinicki T, Sayer AAP. MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty - protocol for a double-blind, randomised controlledproof-of-concept trial. BMJ Open. 2022 Jul; 12(7):e061823

Zhang X, Habiballa L, Aversa Z, Ng YE, Sakamoto AE, Englund DA, Pearsall VM, White TA, Robinson MM, Rivas DA, Dasari S, Hruby AJ, Lagnado AB, Jachim SK, Granic A, Sayer AA, Jurk D, Lanza IR, Khosla S, Fielding RA, Nair KS, Schafer MJ, Passos JF, LeBrasseur NK. Characterization of cellular senescence in aging skeletal muscle. Nature Aging. 2022 Jul 15;2(7):601-615

Granic A, Cooper R, Dodds RM, Hillman SJ, Sayer AA, Robinson SM. Milk intake across adulthood and muscle strength decline from mid- to late life: the MRC National Survey of Health and Development. British Journal of Nutrition; 2022 Jul 07:1-12

Cullinan RJ, Richardson SJ, Yarnall AJ, Burn DJ, Allan LM, Lawson RA. Documentation and diagnosis of delirium in Parkinson's disease. Acta Psychiatrica Scandinavica. 2022 Jun 30;147(5):527-535

Hurst C, Sayer AA. Improving muscle strength and physical function in older people living with sarcopenia and physical frailty: Not all exercise is created equal. Journal of the Royal College of Physicians of Edinburgh. 2022 Jun 17;52(2):166-171

Pinto Pereira SM, Garfield V, Farmaki AE, Tomlinson DJ, Norris T, Fatemifar G, Denaxas S, Finan C, Cooper R. Adiposity and grip strength: a Mendelian randomisation study in UK Biobank. BMC Medicine. 2022 Jun 2;20(1):201.

Cooper R, Tomlinson D, Hamer M, Pinto Pereira SM. Lifetime body mass index and grip strength at age 46 years: the 1970 British Cohort Study.J Cachexia Sarcopenia Muscle. Journal of cachexia, sarcopenia and muscle 2022 May 19; 13:1995-2004

Odland ML, Ismail S, Sepanlou SG, Poustchi H, Sadjadi A, Pourshams A, Marshall T, Witham MD, Malekzadeh R, Davies JI. Multimorbidity and associations with clinical outcomes in a middle-aged population in Iran: a longitudinal cohort study. BMJ Global Health. 2022 May 12;7(5):e007278

Clegg A, Bandeen-Roche K, Farrin A, Forster A, Gill TM, Gladman J, Kerse N, Lindley R, McManus RJ, Melis R, Mujica-Mota R, Raina P, Rockwood K, Teh R, van der Windt D, Witham M. New horizons in evidence-based care for older people: individual participant data meta-analysis. Age and Ageing. 2022 Apr;51(4):afac090

Dodds RM, Heslop P, Jaffar J, Davies K, Noble JM, Shaw FE, Witham MD, Sayer AA. The assessment of sarcopenia and the frailty phenotype in the outpatient care of older people: implementation and typical values obtained from the Newcastle SarcScreen project. European Geriatric Medicine. 2022 Apr 9;13:763-769

Newlands R, Duncan E, Treweek S, Elliott J, Presseau J, Bower P, MacLennan G, Ogden M, Wells M, Witham MD, Young B, Gillies K. The development of theory-informed participant-centred interventions to maximise participant retention in randomised controlled trials. Trials. 2022 Apr 8;23(1):268

Blodgett JM, Cooper R, Davis DHJ, Kuh D and Hardy R. Associations of word memory, verbal fluency, processing speed and crystallised cognitive ability with one-legged balance performance in mid and later life. Journal of Gerontology: Medical Sciences 2022 April 4;77:807-816

Suetterlin KJ, Männikkö R, Matthews E, Greensmith L, Hanna MG, Bostock H, Tan SV. Excitability Properties of Mouse and Human Skeletal Muscle Fibres Compared by Muscle Velocity Recovery Cycles. Neuromuscul Disorders. 2022 Apr; 32(4):347-357

Tsui A, Searle SD, Bowden H, Hoffmann K, Hornby J, Goslett A, Weston-Clarke M, Howes LH, Street R, Perera R, Taee K, Kustermann C, Chitalu P, Razavi B, Magni F, Das D, Kim S, Chaturvedi N, Sampson EL, Rockwood K, Cunningham C, Ely EW, Richardson SJ, Brayne C, Terrera GM, Tieges Z, MacLullich A, Davis D. The effect of baseline cognition and delirium on long-term cognitive impairment and mortality: a prospective population-based study. Lancet Healthy Longevity. 2022 Apr;3(4):e232-e241

Witham MD, Heslop P, Dodds RM, Clegg AP, Hope SV, McDonald C, Smithard D, Storey B, Tan AL, Thornhill A, Sayer AA. Performance of the SarQoL quality of life tool in a UK population of older people with probable sarcopenia and implications for use in clinical trials: findings from the SarcNet registry. BMC Geriatrics. 2022 Apr; 51:368

LACE study group, Achison M, Adamson S, Akpan A, Aspray T, Avenell A, Band MM, Bashir T, Burton LA, Cvoro V, Donnan PT, Duncan GW, George J, Gordon AL, Gregson CL, Hapca A, Henderson E, Hume C, Jackson TA, Kemp P, Kerr S, Kilgour A, Lyell V, Masud T, McKenzie A, McKenzie E, Patel H, Pilvinyte K, Roberts HC, Rossios C, Sayer AA, Smith KT, Soiza RL, Steves CJ, Struthers AD, Sumukadas D, Tiwari D, Whitney J, Witham MD. Effect of perindopril or leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial. J Cachexia Sarcopenia Muscle. Journal of Cachexia Sarcopenia Muscle 2022 Feb 16;13(2):858–871

Hurst C, Robinson SM, Witham MD, Dodds RM, Granic A, Buckland C, De Biase S, Finnegan S, Rochester L, Skelton DA, Sayer AA. Resistance exercise as a treatment for sarcopenia: prescription and delivery. Age Ageing 2022 Feb 12;51(2):afac003

Lawson RA, Richardson SJ, Kershaw D, Davis DHJ, Stephan B, Robinson L, Brayne C, Barnes L, Burn DJ, Yarnall AJ, Taylor JP, Parker S, Allan LM. Evaluation of Bedside Tests of Attention and Arousal Assessing Delirium in Parkinson’s Disease, Dementia, and Older Adults. Journal of Parkinson’s Disease 2022 Feb;12(2):655-665

Blodgett JM, Ventre JP, Mills R, Hardy R and Cooper R. A systematic review of one-legged balance performance and falls risk in community-dwelling adults. Ageing Research Reviews 2022 Jan;73:101501

Zhang J, Bloom I, Dennison EM, Ward KA, Robinson SM, Barker M, Cooper C, Lawrence W.  Understanding influences on physical activity participation by older adults: A qualitative study of community-dwelling older adults from the Hertfordshire Cohort Study, UK. PLoS One. 2022 Jan 25;17(1):e0263050

Granic A, Hurst C, Dismore L, Dodds RM, Witham MD, Robinson SM, Sayer AA.Advanced glycation end products in skeletal muscle health and sarcopenia: a systematic review of observational studies. Mechanisms of Ageing and Development. 2022 Jan:111744

Hayes EJ, Stevenson E, Sayer AA, Granic A, Hurst C. Recovery from resistance exercise in older adults: a protocol for a scoping review. BMJ Open Sport Exerc Med. 2022 Jan; 8(1):e001229

Ni Lochlainn, M. & Robinson, S.  UK Nutrition Research Partnership workshop: Nutrition and frailty—opportunities for prevention and treatment. Nutrition Bulletin. 2022 Jan 6;47:123 –129

Hakeem S, Mendonça N, Aspray T, Kingston A, Martin-Ruiz C, Robinson L, Hill TR. The Association between 25-Hydroxyvitamin D Concentration and Telomere Length in the Very-Old: The Newcastle 85+ Study. Nutrients. 2021 Dec 1;13(12):4341

Cox NJ, Morrison L, Robinson SM, Roberts HC, Ibrahim K. Older individual's perceptions of appetite, its loss, influencing factors and adaptions to poor appetite. A qualitative study. Appetite 2021 Dec;167

Antoun E, Garratt ES, Taddei A, Burton MA, Barton SJ, Titcombe P, Westbury LD, Baczynska A, Migliavacca E, Feige JN, Sydall HE, Dennison E, Dodds R, Roberts HC, Richardson P, Sayer AA, Shaw S, Cooper C, Holbrook JD, Patel HP, Godfrey KM, Lillycrop KA; EpiGen Global Research Consortium. Epigenome-wide association study of sarcopenia: findings from the Hertfordshire Sarcopenia Study (HSS) J Cachexia Sarcopenia Muscle 2022 Feb;13(1):240-253 2021 Epub Dec 2021

Volkert D, Corish CA,  Dardevet D, De Vito G,  Guillet C,  Bader-Mittermaier S,  Robinson S,  Roche HM,  Sayer AA,  Visser M.  Innovative plAnt Protein fibre and Physical activity solutions to address poor appEtite and prevenT undernutrITion in oldEr adults – APPETITE.  Nutrition Bulletin. 2021 Nov 17;46 (4):486-496

Barker FJ, Davies JI, Gomez-Olive FX, Kahn K, Matthews FE, Payne CF, Salomon JA, Tollman SM, Wade AN, Walker RW, Witham MD. Developing and evaluating a frailty index for older South Africans-findings from the HAALSI study. Age and Ageing. 2021 Nov; 50 (6):2167–2173

Stocker R, Shaw J, Taylor GS, Witham MD, West DJ EXercise to Prevent frailty and Loss Of independence in insulin treated older people with DiabetEs (EXPLODE): protocol for a feasibility randomised controlled trial (RCT) BMJ Open. 2021 Nov; 11(12):e048932

Ribeiro A, Suetterlin KJ, Skorupinska I, Tan SV, Morrow JM, Matthews E, Hanna MG, Fialho D The long exercise test as a functional marker of periodic paralysis. Muscle Nerve. 2021 Nov 24

PHOSP-COVID collaborative group.  Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. The Lancet Respiratory Medicine. 2021 Nov;9(11):1275-1287

Hurst C, Murray JC, Granic A, Hillman SJ, Cooper R, Sayer AA, Robinson SM, Dodds RM. Long-term conditions, multimorbidity, lifestyle factors and change in grip strength over 9 years of follow-up: Findings from 44,315 UK biobank participants. Age and Ageing. 2021 Nov; 50 (6): 2222–2229

Payne L, Ghio D, Grey E, Slodkowska-Barabasz J, Harris P, Sutcliffe M, Green S, Roberts HC, Childs C, Robinson S, Gudgin B, Holloway P, Kelly J, Wallis K, Dean O, Aveyard P, Gill P, Stroud M, Little P, Yardley L, Morrison L. Optimising an intervention to support home-living older adults at risk of malnutrition: a qualitative study. BMC Fam Pract. 2021 Nov; 22(1):219

Bockarie T, Odland ML, Wurie H, Ansumana R, Lamin J, Witham M, Oyebode O, Davies J. Correction to: Prevalence and socio-demographic associations of diet and physical activity risk-factors for cardiovascular disease in Bo, Sierra Leone. BMC Public Health 21 Oct 7, 2021:1806

Cooper R, Shkolnikov VM, Kudryavtsev A, Malyutina S, Ryabikov A, Hopstock L, Johansson J, Cook S, Leon DA and Strand BH. Between-study differences in grip strength: a comparison of Norwegian and Russian adults aged 40-69 years. Journal of Cachexia, Sarcopenia and Muscle 2021 Oct;12:2091-2100

Lees JS, Rankin AJ, Gillis KA, Zhu LY, Mangion K, Rutherford E, Roditi GH, Witham MD, Chantler D, Panarelli M, Jardine AG, Mark PB. The ViKTORIES trial: a randomised, double-blind, placebo-controlled trial of vitamin K supplementation to improve vascular health in kidney transplant recipients. American Journal of Transplantation 2021 Oct;21:3356–3368

Newlands R, Duncan E, Presseau J, Treweek S, Lawrie L, Bower P, Elliott J, Francis J, MacLennan G, Ogden M, Wells M, Witham MD, Young B, Gillies K. Why trials lose participants: a multi-trial investigation of participants' perspectives using the theoretical domains framework. Journal of Clinical Epidemiology 2021 Sep;137:1-13

Witham MD, Heslop P, Dodds RM, Clegg AP, Hope SV, McDonald C, Smithard D, Storey B, Tan AL, Thornhill A, Sayer AA. Developing a UK sarcopenia registry: recruitment and baseline characteristics of the SarcNet pilot. Age and Ageing. 2021 Sep; 50 (5):1762–1769

Wade AN, Payne CF, Berkman L, Chang A, Gómez-Olivé FX, Kabudula C, Kahn K, Salomon JA, Tollman S, Witham M, Davies J. Multimorbidity and mortality in an older, rural black South African population cohort with high prevalence of HIV findings from the HAALSI Study. BMJ Open. 2021 Sep;11(9):e047777

Suetterlin K, Matthews E, Sud R, McCall S, Fialho D, Burge J, Jayaseelan D, Haworth A, Sweeney MG, Kullmann DM, Schorge S, Hanna MG, Männikkö R. Translating genetic and functional data into clinical practice: a series of 223 families with myotonia. Brain. 2021 Sep;145(2):607-620

Sivaharan A, Boylan L, Witham MD, Nandhra S. Sarcopenia in patients undergoing lower limb bypass surgery is associated with higher mortality and major amputation rates. Annals of Vascular surgery. 2021 Aug;75:227-236.

Hayes LD, Elliott BT, Yasar Z, Bampouras TM, Sculthorpe NF, Sanal-Hayes NEM, Hurst C.High Intensity Interval Training (HIIT) as a Potential Countermeasure for Phenotypic Characteristics of Sarcopenia: A Scoping Review. Frontiers in Physiology. 2021 Aug; 12:715044

Buttgereit T, Palmowski A, Forsat N, Boers M, Witham MD, Rodondi N, Moutzouri E, Navidad AJQ, Van't Hof AWJ, van der Worp B, Coll-Planas L, Voshaar M, de Wit M, da Silva J, Stegemann S, Bijlsma JW, Koeller M, Mooijaart S, Kearney PM, Buttgereit F.  Barriers and potential solutions in the recruitment and retention of older patients in clinical trials-lessons learned from six large multicentre randomized controlled trials. Age & Ageing. 2021 Jul 19; 50 (6): 1988–1996

Bloom I, Pilgrim A, Jameson KA, Dennison EM, Sayer AA, Roberts HC, Cooper C, Ward KA, Robinson SM.The relationship of nutritional risk with diet quality and health outcomes in community-dwelling older adults. Aging Clinical and Experimental Research. 2021 Jul 13; 33:2767–2776

Gordon A, Witham MD, Henderson E, Harwood R, Masud T. Research into ageing and frailty. Future Healthcare Journal. 2021 Jul 21;8(2):e237-e242

Ni Lochlainn M, Cox NJ, Wilson T, Hayhoe RPG, Ramsay SE, Granic A, Isanejad M, Roberts HC, Wilson D, Welch C, Hurst C, Atkins JL, Mendonça N, Horner K, Tuttiett ER, Morgan Y, Heslop P, Williams EA, Steves CJ, Greig C, Draper J, Corish CA, Welch A, Witham MD, Sayer AA, Robinson S. Nutrition and Frailty: Opportunities for Prevention and Treatment. Nutrients. 2021 Jul 9;13 (7):2349

Lees JS, Mark PB, Witham MD. Vitamin K and vascular calcification. Current Opinion in Nephrology and Hypertension. Current Opinion in Nephrology and Hypertension 2021 Jul;30(4):430-436.

Caulfield L, Heslop P, Walesby KE, Sumukadas D, Sayer AA, Witham MD. Effect of Angiotensin System Inhibitors on Physical Performance in Older People - A Systematic Review and Meta-Analysis Journal of the American Medical Directors 2021 June; 22(6):1215-1221

Doherty WJ, Stubbs TA, Chaplin A, Langford S, Sinclair N, Ibrahim K, Reed MR, Sayer AA, Witham MD, Sorial AK. Implementing grip strength assessment in hip fracture patients: a feasibility project. Journal of Frailty, Sarcopenia & Falls. 2021 Jun; 6(2):66-78

Geriatric Medicine Research Collaborative. Retrospective delirium ascertainment from case notes: a retrospective cohort study. BMJ Open. 2021 May 28; 11(5): e042440

Robinson SM, Westbury L.D, Ward K, Sydall H, Cooper R, Cooper C, Sayer AA. Is lifestyle change around retirement associated with better physical performance in older age?: insights from a longitudinal cohort. European Journal of Ageing. 2021 May 27; 18: 513–521.

Treweek S, Banister K, Bower P, Cotton S, Devane D, Gardner HR, Isaacs T, Nestor G, Oshisanya A, Parker A, Rochester L, Soulsby I, Williams H, Witham MD. Developing the INCLUDE Ethnicity Framework– a tool to help trialists design trials that better reflect the communities they serve. Trials 22, 2021 May 10; 337

Chungath RR, Witham MD, Clarke CL, Hutcheon A, Gandy S, Gingles C, Priba L, Nicholas SR, Cavin I, Sumukadas D, Struthers AD, George J. Association between mitochondrial function measured by 31P Magnetic Resonance Spectroscopy and physical performance in older people with functional impairment.  JCSM Clinical Reports 2021 May; 6(3):71-79

Soysal P, Hurst C, Demurtas J, Firth J, Howden R, Yang L, Tully MA, Koyanagi A, Ilie PC, López-Sánchez GF, Schwingshackl L, Veronese N, Smith L. Handgrip strength and health outcomes: Umbrella review of systematic reviews with meta-analyses of observational studies Journal of Sport and Health Science 2021 May; 10(3); 290-295

Geriatric Medicine Research Collaborative. Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study. Age Ageing 2021 May; 50(3):617-630

Nikpour Hernandez N, Ismail S, Heang H, van Pelt M, Witham MD, Davies JI. An innovative model for management of cardiovascular disease risk factors in the low resource setting of Cambodia. Health Policy and Planning 2021 May; 36(4):397–406

Richardson SJ, Davis DHJ, Stephan BCM, Robinson L, Brayne C, Barnes LE, Taylor JP, Parker SG, Allan LM.  Recurrent delirium over 12 months predicts dementia: results of the Delirium and Cognitive Impact in Dementia (DECIDE) study.  Age and Ageing. 2021 May;50: 914-920

Richardson SJ, Lawson RA, Davis DHJ, Stephan B, Robinson L, Matthews FM, Brayne C, Barnes L, Taylor JP, Parker S, Allan LM.  Hospitalisation without delirium is not associated with cognitive decline in a population-based sample of older people – results from a nested, longitudinal cohort study. Age and Ageing 2021 May; 50(5):1675–1681

Witham MD, Dodds RM.  Hip fracture and sarcopenia – the need for a new paradigm in therapeutics trials for older people? The Lancet - Healthy Longevity 2021 May; 2: 234-235

Robinson S, Granic A, Sayer AA. Micronutrients and sarcopenia: current perspectives. Proceedings of the Nutrition Society. 2021 May;80(3):311-318

Suetterlin KJ, Tan SV, Mannikko R, Phadke R, Orford M, Eaton S, Sayer AA, Grounds MD, Matthews E, Greensmith L, Hanna MG.  Ageing contributes to phenotype transition in a mouse model of periodic paralysis. JCSM Rapid Communications. 2021 May; 4: 245–259

Christodoulou M, Aspray TJ, Schoenmakers I. Vitamin D Supplementation for Patients with Chronic Kidney Disease: A Systematic Review and Meta-analyses of Trials Investigating the Response to Supplementation and an Overview of Guidelines. Calcified Tissue International. 2021 Apr; 109(2):157-178.

Witham MD, Achison M, Aspray TJ, Avenell A, Band MM, Donnan PT, George J, Hapca A, Hume C, Kemp P, Pilvinyte K, Sayer AA, Smith KT, Struthers AD, Sumukadas D. Recruitment strategies for sarcopenia trials – lessons from the LACE randomised controlled trial. JCSM Rapid Communications 2021 Apr 5;4:93–102

Denison HJ, Jameson KA, Sayer AA, Patel HP, Edwards MH, Arora T, Dennison EM, Cooper C, Baird J. Poor sleep quality and physical performance in older adults Sleep Health 2021 Apr; 7(2): 205-211

Lim SX, Colega MT, M Ayob MN, Robinson SM, Godfrey KM, Bernard JY, Lee YS, Tan KH, Yap F, Shek LP, Chong YS, Eriksson JG, Chan JK, Chan SY, Chong MF. Identification and reproducibility of dietary patterns assessed with a FFQ among women planning pregnancy. Public Health Nutrition. 2021 Mar 22;24(9):2437-2446

Smith G, Avenell A, Band MM, Hampson G, Lamb EJ, Littleford RC, McNamee P, Soiza RL, Sumukadas D, Witham MD. Associations between frailty, physical performance, and renal biomarkers in older people with advanced chronic kidney disease European Geriatric Medicine. 2021 Mar 17;12(5):943-952

Brinkmann B, Payne CF, Kohler IV, Harling G, Davies JI, Witham MD, Siedner MJ, Sie A, Bountogo M, Ouermi L, Coulibaly B, Barnighausen T, Junghanns J. Impairment in Activities of Daily Living and unmet need for care among older adults: A population-based study from Burkina Faso. The Journals of Gerontology Series B 2021 Mar 14;76(9):1880-1892

Hand A, Oates LL, Gray WK, Dismore LL, Baker K, Naisby J, Walker RW. Understanding Caregiver Strain in Parkinsonism-A Mixed Methods Approach. Journal of Geriatric Psychiatry and Neurology 2021 Mar 2; 891988721996819

Bolland MJ, Avenell A, Smith K, Witham MD, Grey A.  Vitamin D supplementation and testing in the UK: costly but ineffective? BMJ 2021 Mar; 372

Tullo E, Dodds RM, Birkbeck M, Habiballa L, Sayer AA. Paving the translational ageing research pathway-training the next generation of researchers.  Age and Ageing. 2021 Mar; 50: 362-365

Doherty WJ, Stubbs TA, Chaplin A, Reed MR, Sayer AA, Witham MD, Sorial AK. Prediction of Postoperative Outcomes Following Hip Fracture Surgery: Independent Validation and Recalibration of the Nottingham Hip Fracture Score Journal of The American Medical Directors Association 2021 Mar; 22(3):663-669

Forster J, Tullo E, Wakeling L, Gilroy RG. Involving older people in inclusive educational research. Journal of Aging Studies 2021 Mar; 56:100906

Richardson S, Murray J, Davis D, Stephan BCM, Robinson L, Brayne C, Barnes L, Parker S, Sayer A, Dodds R, Allan L. Delirium and delirium severity predict the trajectory of the Hierarchical Assessment of Balance and Mobility (HABAM) in hospitalised older people: findings from the DECIDE Study. Journal of Gerontology 2021 Mar, Series A

Witham MD, Gordon AL, Henderson EJ, Harwood RH. Pandemic research for older people: doing it better next time. Age and Ageing 2021 Mar;50(2):276–278.

McKeaveney C, Slee A, Adamson G, Davenport A, Farrington K, Fouque D, Kalanter-Zadeh K, Mallett J, Maxwell AP, Mullan R, Noble H, O'Donoghue D, Porter S, Seres DS, Shields J, Witham M, Reid J.Erratum to: Using a generic definition of cachexia to understand clinical characteristics and mortality in patients with kidney disease receiving haemodialysis: a longitudinal (pilot) study.  Nephrology Dialysis Transplantation 2021 Feb 28;36(8):e1554.

Birkbeck MG, Blamire AM, Whittaker RG, Sayer AA, Dodds RM. The role of novel motor unit magnetic resonance imaging (MUMRI) to investigate motor unit activity in ageing skeletal muscle. Journal of Cachexia Sarcopenia and Muscle 2021 Feb; 12(1): 17-29

Walker H, De Souza N, Hapca S, Witham MD, Bell S. Effect of multiple episodes of acute kidney injury on mortality: an observational study. Clinical Kidney Journal 2021 Feb 10; 14(2): 696–703

Lawson RA, Richardson SJ (joint first author), Kershaw D, Davis DHJ, Stephan B, Robinson L, Brayne C, Barnes L, Burn DJ, Yarnall AJ, Taylor JP, Parker S, Allan LM. Evaluation of Bedside Tests of Attention and Arousal Assessing Delirium in Parkinson’s Disease, Dementia, and Older Adults. Journal of Parkinson’s Disease 2021 Feb

Dodds RM, Murray JC, Granic A, Hurst C, Uwimpuhwe G , Richardson S, Brayne C,  Matthews FE, Sayer AA.  Prevalence and factors associated with poor performance in the 5-chair stand test: findings from the Cognitive Function and Ageing Study II and proposed Newcastle protocol for use in the assessment of sarcopenia.  Journal of Cachexia, Sarcopenia and Muscle 2021 Jan;12(2):308-318

Brinkmann B, Payne CF, Kohler I, Harling G, Davies J, Witham M, Siedner MJ, Sie A, Bountogo M, Ouermi L, Coulibaly B, Barnighausen T. Depressive symptoms and cardiovascular disease: a population-based study of older adults in rural Burkina Faso. BMJ Open 2020 Dec; 10: e038199

Cox NJ, Lim SE, Howson F, Moyses H, Ibrahim K, Sayer AA, Roberts HC, Robinson SM. Poor Appetite Is Associated with Six Month Mortality in Hospitalised Older Men and Women The Journal of Nutrition, Health & Aging 2020 Dec; 24: 1107–1110

Ignatowicz A, Odland ML, Bockarie T, Wurie H, Ansumana R, Kelly AH, Willott C, Witham MD, Davies JI. Knowledge and understanding of cardiovascular disease risk factors in Sierra Leone: perceptions of patients and community leaders. BMJ Open 2020 Dec; 10: e038523

Rutherford E, Ireland S, Mangion K, Stewart GA, MacGregor MS, Roditi G, Woodward R, Gandy SJ, Houston JG, Jardine AG, Rauchhaus P, Witham MD, Mark PB, Struthers AD.  A randomized, controlled trial of the effect of allopurinol on left ventricular mass index in hemodialysis patients.  Kidney International Reports 2020 Dec 4; 6(1):146-155

van Dijk M, Cullum A, Swan G, Peacock E, Fine G, Robinson S, McArdle H, Walls A, Walsh S; Scientific Advisory Committee on Nutrition (SACN). An overview of the Scientific Advisory Committee on Nutrition's position statement on nutrition and older adults living in the community. British Journal of Nutrition. 2020 Dec; 126:1164 – 1167

Richardson SJ, Carroll CB, Close J, Gordon AL, O'Brien J, Quinn TJ, Rochester L, Sayer AA, Shenkin SD, Velde NVD, Woo J, Witham MD. Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities Age and Ageing 2020 Nov; 49: 901-906

Cox LS, Bellantuono I, Lord JM, Sapey E, Mannick J, Partridge L, Gordon AL, Steves CJ, Witham MD. Tackling immunosenescence to improve COVID-19 outcomes and vaccine response in older adults. Lancet Healthy Longevity 2020 Nov; 1: 55-7

Smith KA, Bradbury K, Essery R, Pollet S, Mowbray F, Slodkowska-Barabasz J, Denison-Day J, Hayter V, Kelly J, Somerville J, Zhang J, Grey E, Western M, Ferrey AE, Krusche A, Stuart B, Mutrie N, Robinson S, Yao GL, Griffiths G, Robinson L, Rossor M, Gallacher J, Griffin S, Kendrick T, Rathod S, Gudgin B, Phillips R, Stokes T, Niven J, Little P, Yardley L. The Active Brains Digital Intervention to Reduce Cognitive Decline in Older Adults: Protocol for a Feasibility Randomized Controlled Trial. JMIR Research Protocols. 2020 Nov; 9: e18929

McKeaveney C, Slee A, Adamson G, Davenport A, Farrington K, Fouque D, Kalanter-Zadeh K, Mallett J, Maxwell AP, Mullan R, Noble H, O'Donoghue D, Porter S, Seres DS, Shields J, Witham M, Reid J. Using a generic definition of cachexia in patients with kidney disease receiving haemodialysis: a longitudinal (pilot) study. Nephrology, Dialysis, Transplantation 2020 Nov 5; 36: 1919–1926

Witham MD, Anderson E, Carroll CB, Dark PM, Down K, Hall AS, Knee J, Maher ER, Maier RH, Mountain GA, Nestor G, O'Brien JT, Oliva L, Wason J, Rochester L, Group UNCIS. Ensuring that COVID-19 research is inclusive: guidance from the NIHR INCLUDE project BMJ Open 2020 Nov; 10: e043634

Witham MD, Clarke CL, Hutcheon A, Gingles C, Gandy S, Priba L, Nicholas RS, Cavin I, Sumukadas D, Struthers AD, George J. Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function: a randomised controlled trial Age and Ageing 2020 Nov; 49: 1003-1010

Witham MD, Lees JS, White M, Band M, Bell S, Chantler DJ, Ford I, Fulton RL, Kennedy G, Littleford RC, McCrea IV, McGlynn D, Panarelli M, Ralston MR, Rutherford E, Severn A, Thomson N, Traynor JP, Struthers AD, Wetherall K, Mark PB. Vitamin K Supplementation to Improve Vascular Stiffness in CKD: The K4Kidneys Randomized Controlled Trial Journal of The American Society of Nephrology 2020 Oct; 31: 2434-2445

nskip H, Crozier S, Baird J, Hammond J, Robinson S, Cooper C, Godfrey K, Group USWSS. Measured weight in early pregnancy is a valid method for estimating pre-pregnancy weight Journal of Developmental Origins of Health and Disease 2020 Oct; 1-9

Odland ML, Bockarie T, Wurie H, Ansumana R, Lamin J, Nugent R, Bakolis I, Witham M, Davies J. Prevalence and access to care for cardiovascular risk factors in older people in Sierra Leone: a cross-sectional survey BMJ Open 2020 Sep; 10: e038520

Yarnall AJ, Granic A, Waite S, Hollingsworth KG, Warren C, Vincent AE, Turnbull DM, Taylor RW, Dodds RM, Sayer AA. The feasibility of muscle mitochondrial respiratory chain phenotyping across the cognitive spectrum in Parkinson's disease Experimental Gerontology 2020 Sep; 138: 110997

Biase SD, Cook L, Skelton DA, Witham M, Hove RT. The COVID-19 rehabilitation pandemic Age and Ageing 2020 Sep; 49: 696-700

Young S, Tullo E . From criminology to gerontology: case studies of experiential authenticity in higher education. Journal of Perspectives in Applied Academic Practice 2020 Sep 1; 8: 127-34

Granic A, Martin-Ruiz C, Dodds RM, Robinson L, Spyridopoulos I, Kirkwood TB, Zglinicki TV, Sayer AA. Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study Mechanisms of Ageing and Development 2020 Sep; 190:111321

Tomaz SA, Davies JI, Micklesfield LK, Wade AN, Kahn K, Tollman SM, Draper CE, Witham MD. Self-Reported Physical Activity in Middle-Aged and Older Adults in Rural South Africa: Levels and Correlates International Journal of Environmental Research and Public Health 2020 Aug; 17: 6325

Witham MD, Anderson E, Carroll C, Dark PM, Down K, Hall AS, Knee J, Maier RH, Mountain GA, Nestor G, Oliva L, Prowse SR, Tortice A, Wason J, Rochester L, group UIW. Developing a roadmap to improve trial delivery for under-served groups: results from a UK multi-stakeholder process Trials 2020 Aug; 21: 694

Granic A, Dismore L, Hurst C, Robinson SM, Sayer AA. Myoprotective Whole Foods, Muscle Health and Sarcopenia: A Systematic Review of Observational and Intervention Studies in Older Adults Nutrients 2020 Jul 28; 12: 2257

Granic A, Hurst C, Dismore L, Stevenson E, Sayer AA, Aspray T. Feasibility and acceptability of a milk and resistance exercise intervention to improve muscle function in community-dwelling older adults (MIlkMAN): Pilot study PloS ONE 2020 Jul 10; 15: e0235952

Slee A, McKeaveney C, Adamson G, Davenport A, Farrington K, Fouque D, Kalantar-Zadeh K, Mallett J, Maxwell AP, Mullan R, Noble H, O'Donoghue D, Porter S, Seres DS, Shields J, Witham M, Reid J. Estimating the Prevalence of Muscle Wasting, Weakness, and Sarcopenia in Hemodialysis Patients Journal of Renal Nutrition2020 Jul; 30: 313-321

Heslop PA, Davies K, Sayer A, Witham M. Making consent for electronic health and social care data research fit for purpose in the 21st century BMJ Health & Care Informatics 2020 Jul; 27: e100128

Mendonça N, Kingston A, Granic A, Hill TR, Mathers JC, Jagger C. Contribution of protein intake and its interaction with physical activity to transitions between disability states and to death in very old adults: the Newcastle 85+ Study. European Journal of Nutrition 2020 July 10; 59: 1909-1918

Lees JS, Mangion K, Rutherford E, Witham MD, Woodward R, Roditi G, Hopkins T, Brooksbank K, Jardine AG, Mark PB. Vitamin K for kidney transplant organ recipients: investigating vessel stiffness (ViKTORIES): study rationale and protocol of a randomised controlled trial Open Heart 2020 Jul 15; 7: e001070

Tschiderer L, Seekircher L, Klingenschmid G, Izzo R, Baldassarre D, Iglseder B, Calabresi L, Liu J, Price JF, Bae J, Brouwers FP, Groot ED, Schmidt C, Bergström G, Aşçi G, Gresele P, Okazaki S, Kapellas K, Landecho MF, Sattar N, Agewall S, Zou Z, Byrne CD, Nanayakkara PWB, Papagianni A, Witham MD, Bernal E, Ekart R, Agtmael MAV, Neves MF, Sato E, Ezhov M, Walters M, Olsen MH, Stolić R, Zozulińska-Ziółkiewicz DA, Hanefeld M, Staub D, Nagai M, Nieuwkerk PT, Huisman MV, Kato A, Honda H, Parraga G, Magliano D, Gabriel R, Rundek T, Espeland MA, Kiechl S, Willeit J, Lind L, Empana JP, Lonn E, Tuomainen T, Catapano A, Chien K, Sander D, Kavousi M, Beulens JWJ, Bots ML, Sweeting MJ, Lorenz MW, Willeit P, Proof-ATHERO Study Group U. The Prospective Studies of Atherosclerosis (Proof-ATHERO) Consortium: Design and Rationale Gerontology 2020 Jul; 66: 447-459

Cox NJ, Morrison L, Ibrahim K, Robinson SM, Sayer AA, Roberts HC. New horizons in appetite and the anorexia of ageing Age and Ageing 2020 Jul; 49:526-534

Moore SA, Hrisos N, Errington L, Rochester L, Rodgers H, Witham M, Sayer AA. Exercise as a treatment for sarcopenia: an umbrella review of systematic review evidence Physiotherapy 2020 Jun; 107: 189-201

Bell S, James MT, Farmer CKT, Tan Z, Souza ND, Witham MD. Development and external validation of an acute kidney injury risk score for use in the general population Clinical Kidney Journal 2020 Jun; 13: 402-412

Harling G, Payne CF, Davies JI, Gomez-Olive FX, Kahn K, Manderson L, Mateen FJ, Tollman SM, Witham MD.Impairment in activities of daily living, care receipt and unmet needs in a middle-aged and older rural South African population: findings from the HAALSI study. Journal of Aging and Health 2020 June; 32: 296-307 

Willeit P, Tschiderer L, Allara E, Reuber K, Seekircher L, Gao L, Liao X, Lonn E, Gerstein HC, Yusuf S, Brouwers FP, Asselbergs FW, Gilst WV, Anderssen SA, Grobbee DE, Kastelein JJP, Visseren FLJ, Ntaios G, Hatzitolios AI, Savopoulos C, Nieuwkerk PT, Stroes E, Walters M, Higgins P, Dawson J, Gresele P, Guglielmini G, Migliacci R, Ezhov M, Safarova M, Balakhonova T, Sato E, Amaha M, Nakamura T, Kapellas K, Jamieson LM, Skilton M, Blumenthal JA, Hinderliter A, Sherwood A, Smith PJ, Agtmael MAV, Reiss P, Vonderen MGAV, Kiechl S, Klingenschmid G, Sitzer M, Stehouwer CDA, Uthoff H, Zou Z, Cunha AR, Neves MF, Witham MD, Park H, Lee M, Bae J, Bernal E, Wachtell K, Kjeldsen SE, Olsen MH, Preiss D, Sattar N, Beishuizen E, Huisman MV, Espeland MA, Schmidt C, Agewall S, Ok E, Aşçi G, Groot ED, Grooteman MPC, Blankestijn PJ, Bots ML, Sweeting MJ, Thompson SG, Lorenz MW, Groups UPATPS. Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100 667 Patients Circulation 2020 June 17; 142: 621-642

Wright CM, Lessa A, Garcia A, Emmett P, Crozier S, Robinson S, Godfrey KM. Early introduction of solid feeding and early cessation of breastfeeding Maternal & Child Nutrition 2020 June; 16: e13049

Witham MD, Band M, Chong H, Donnan PT, Hampson G, Hu MK, Littleford R, Lamb E, Kalra PA, Kennedy G, McNamee P, Plews D, Rauchhaus P, Soiza RL, Sumukadas D, Warwick G, Avenell A. Sodium bicarbonate to improve physical function in patients over 60 years with advanced chronic kidney disease: the BiCARB RCT Health Technology Assessment  2020 June; 24:1-90

Dismore L, Hurst C, Sayer AA, Stevenson E, Aspray T, Granic A.Study of the Older Adults' Motivators and Barriers Engaging in a Nutrition and Resistance Exercise Intervention for Sarcopenia: An Embedded Qualitative Project in the MIlkMAN Pilot Study Gerontology and Geriatric Medicine 2020 May 19; 6

Granic A, Hurst C, Dismore L, Aspray T, Stevenson E, Witham MD, Sayer AA, Robinson S. Milk for Skeletal Muscle Health and Sarcopenia in Older Adults: A Narrative Review Clinical Interventions in Aging 2020 May; 15:695-714

Witham MD, Wason J, Dodds R, Sayer AA. Developing a composite outcome measure for frailty prevention trials - rationale, derivation and sample size  comparison with other candidate measures BMC Geriatrics 2020 Mar 25; 20: 113

Witham MD, Band M, Ahmed A, Almond MK, Balasubramaniam G, Basnayake K et al; the BiCARB study group. Clinical and cost-effectiveness of oral sodium bicarbonate therapy for older patients with chronic kidney disease and low-grade acidosis (BiCARB): a pragmatic randomised, double-blind, placebo-controlled trial BMC Medicine 2020 Apr; 18: 91

Garrard JW, Cox NJ, Dodds RM, Roberts HC, Sayer AA. Comprehensive geriatric assessment in primary care: a systematic review Aging Clinical and Experimental Research 2020 Apr 9; 32:197-205

Hoozon J, Hutchinson J, Warthon-Medina M, Hancock N, Greathead K, Knowles B, Vargas-Garcia E, Gibson LE, Bush LA, Margetts B, Robinson S, Ness A, Alwan NA, Wark PA, Roe M, Finglas P, Steer T, Page P, Johnson L, Roberts K, Amoutzopoulos B, Burley VJ, Greenwood DC, Cade JE. A systematic review of reviews identifying UK validated dietary assessment tools for inclusion on an interactive guided website for researchers: www.nutritools.org Critical Reviews in Food Science and Nutrition 2020 Apr; 60:1265-1289

Odland ML, Payne C, Witham MD, Siedner MJ, Bärnighausen T, Bountogo M, Coulibaly B, Geldsetzer P, Harling G, Manne-Goehler J, Ouermi L, Sie A, Davies JI. Epidemiology of multimorbidity in conditions of extreme poverty: a population-based study of older adults in rural Burkina Faso BMJ Global Health 2020 Mar 27; 5: e002096

Witham MD, Chawner M, Biase SD, Offord N, Todd O, Clegg A, Sayer AA. Content of exercise programmes targeting older people with sarcopenia or frailty - findings from a UK survey Journal of Frailty, Sarcopenia and Falls 2020 Mar; 5: 17-23

Tullo E, Dodds RM, Birkbeck M, Habiballa L, Sayer AA. Paving the translational ageing research pathway—training the next generation of researchers Age and Ageing 2020 Mar;50(2):362-365

Dodds RM, Murray JC, Robinson SM, Sayer AA. The identification of probable sarcopenia in early old age based on the SARC-F tool and clinical suspicion: findings from the 1946 British birth cohort European Geriatric Medicine 2020 Mar 19; 11: 433-441

Lim S, Ibrahim K, Dodds R, Purkis A, Baxter M, Rogers A, Sayer AA, Roberts HC. Physical activity in hospitalised older people: the feasibility and acceptability of a volunteer-led mobility intervention in the SoMoVe™ study Age and Ageing 2020 Mar; 49:283-291

Carter SA, Parsons CM, Robinson SM, Harvey NC, Ward KA, Cooper C, Dennison EM. Infant milk feeding and bone health in later life: findings from the Hertfordshire cohort study Osteoporosis International 2020 Feb 15; 31: 709-714

Todd OM, Burton JK, Dodds RM, Hollinghurst J, Lyons RA, Quinn TJ, Schneider A, Walesby KE, Wilkinson C, Conroy S, Gale CP, Hall M, Walters K, Clegg AP. New Horizons in the use of routine data for ageing research Age and Ageing 2020 Feb 10; 49: 716-722

Shea C, Witham MD. Association between the Use of Angiotensin-Blocking Medications with Hip Fracture and Death in Older People The Journal of Frailty & Aging 2020 Feb; 9: 107-110

Bloom I, Welch L, Vassilev I, Rogers A, Jameson K, Cooper C, Robinson S, Baird J. Findings from an exploration of a social network intervention to promote diet quality and health behaviours in older adults with COPD: a feasibility study Pilot and Feasibility Studies 2020 Feb 6; 6:15

Dodds RM, Granic A, Robinson SM, Sayer AA. Sarcopenia, long-term conditions, and multimorbidity: findings from UK Biobank participants Journal of Cachexia, Sarcopenia and Muscle 2020 Feb; 11: 62-68

Lessa A, Garcia AL, Emmett P, Crozier S, Robinson S, Godfrey KM, Wright CM. Does early introduction of solid feeding lead to early cessation of breastfeeding? Maternal and Child Nutrition 2020 Jan 29;16: e12944

Aspray TJ.Vitamin D in Musculoskeletal Health and Beyond Calcified Tissue International 2020 Jan 8; 106:1-2

Granic A, Mendonça N, Sayer AA, Hill TR, Davies K, Siervo M, Mathers JC, Jagger C. Effects of dietary patterns and low protein intake on sarcopenia risk in the very old: The Newcastle 85+ study Clinical Nutrition 2020 Jan; 39:166-173

Collaborative UGMR. Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: results of a prospective multi-centre study on World Delirium Awareness Day BMC medicine 2019 Dec 14;1(17):229

Crozier SR, Godfrey KM, Calder PC, Robinson SM, Inskip HM, Baird J, Gale CR, Cooper C, Sibbons CM, Fisk HL, Burdge GC. Vegetarian Diet during Pregnancy Is Not Associated with Poorer Cognitive Performance in Children at Age 6–7 Years Nutrients 2019 Dec 11;12(11):3029

Dodds RM, Granic A, Robinson SM, Sayer AA. Sarcopenia, long‐term conditions, and multimorbidity: findings from UK Biobank participants Journal of Cachexia, Sarcopenia and Muscle 2019 Dec 30;0(0):10.1002/jcsm.12503

Dodds RM. Letter to the Editor JCSM Rapid Communications 2019 Dec 13

Migliavacca E, Tay SKH, Patel HP, Sonntag T, Civiletto G, McFarlane C, Forrester T, Barton SJ, Leow MK, Antoun E, Charpagne A, Chong YS, Descombes P, Feng L, Francis-Emmanuel P, Garratt ES, Giner MP, Green CO, Karaz S, Kothandaraman N, Marquis J, Metairon S, Moco S, Nelson G, Ngo S, Pleasants T, Raymond F, Sayer AA, Sim CM, Slater-Jefferies J, Syddall HE, Tan PF, Titcombe P, Vaz C, Westbury LD, Wong G, Yonghui W, Cooper C, Sheppard A, Godfrey KM, Lillycrop KA, Karnani N, Feige JN. Mitochondrial oxidative capacity and NAD⁺ biosynthesis are reduced in human sarcopenia across ethnicities Nature communications 2019 Dec 20;1(10):5808

Robinson S, Granic A, Sayer AA. Nutrition and Muscle Strength, As the Key Component of Sarcopenia: An Overview of Current Evidence Nutrients 2019 Dec 3;12(11):2942

Statham LA, Aspray TJ. Odanacatib: the best osteoporosis treatment we never had? The lancet. Diabetes & endocrinology 2019 Dec;12(7):888-889

Mendonça N, Kingston A, Granic A, Jagger C. Protein intake and transitions between frailty states and to death in very old adults: the Newcastle 85+ study Age and ageing 2019 Nov 11;1(49):32-38

Potter H, Chial HJ, Caneus J, Elos M, Elder N, Borysov S, Granic A. Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders Frontiers in genetics 2019 Nov 7;0(10):1092

Shannon OM, Stephan BCM, Granic A, Lentjes M, Hayat S, Mulligan A, Brayne C, Khaw K, Bundy R, Aldred S, Hornberger M, Paddick S, Muniz-Tererra G, Minihane A, Mathers JC, Siervo M. Mediterranean diet adherence and cognitive function in older UK adults: the European Prospective Investigation into Cancer and Nutrition–Norfolk (EPIC-Norfolk) Study The American Journal of Clinical Nutrition 2019 Oct;4(110):938-948

Blackstock S, Witham MD, Wade AN, Crampin A, Beran D, Ogle GD, Davies JI. Ability of verbal autopsy data to detect deaths due to uncontrolled hyperglycaemia: testing existing methods and development and validation of a novel weighted score BMJ open 2019 Oct 18;10(9):e026331

Granic A, Hurst C, Dismore L, Davies K, Stevenson E, Sayer AA, Aspray T. Milk and resistance exercise intervention to improve muscle function in community-dwelling older adults at risk of sarcopenia (MIlkMAN): protocol for a pilot study BMJ Open 2019 Oct 2019;10(9):e031048

Offord NJ, Clegg A, Turner G, Dodds RM, Sayer AA, Witham MD. Current practice in the diagnosis and management of sarcopenia and frailty – results from a UK-wide survey Journal of Frailty, Sarcopenia and Falls 2019 Sep;0(0):71-77

Caneus J, Granic A, Chial HJ, Potter H. Using fluorescence in situ hybridization (FISH) analysis to measure chromosome instability and mosaic aneuploidy in neurodegenerative diseases. Genomic Mosaicism in Neurons and Other Cell Types. 2017 Sep 9:329-59

Hill TR, Verlaan S, Biesheuvel E, Eastell R, Bauer JM, Bautmans I, Brandt K, Donini LM, Maggio M, Mets T, Seal CJ, Wijers SL, Sieber C, Cederholm T, Aspray TJ, Consortium UP. A Vitamin D, Calcium and Leucine-Enriched Whey Protein Nutritional Supplement Improves Measures of Bone Health in Sarcopenic Non-Malnourished Older Adults: The PROVIDE Study Calcified tissue international 2019 Jul 23;4(105):383-391

Mendonça N, Kingston A, Granic A, Hill TR, Mathers JC, Jagger C. Contribution of protein intake and its interaction with physical activity to transitions between disability states and to death in very old adults: the Newcastle 85+ Study European journal of nutrition 2019 Jul 10;0(0):10.1007/s00394-019-02041-1

Granic A, Davies K, Dodds RM, Duncan R, Uwimpuhwe G, Pakpahan E, Robinson S, Sayer AA. Factors associated with change in self-reported physical activity in the very old: The Newcastle 85+ study PLOS ONE 2019 Jul 16;7(14):e0218881

Harris PS, Payne L, Morrison L, Green SM, Ghio D, Hallett C, Parsons EL, Aveyard P, Roberts HC, Sutcliffe M, Robinson S, Slodkowska-Barabasz J, Little PS, Stroud MA, Yardley L. Barriers and facilitators to screening and treating malnutrition in older adults living in the community: a mixed-methods synthesis BMC family practice 2019 Jul 15;1(20):100

Witham MD, Price RJG, Band MM, Hannah MS, Fulton RL, Clarke CL, Donnan PT, McNamee P, Cvoro V, Soiza RL. Effect of Vitamin K2 on Postural Sway in Older People Who Fall: A Randomized Controlled Trial Journal of the American Geriatrics Society 2019 June;10(67):2102-2107

Cruz-Jentoft AJ, Sayer AA. Sarcopenia The Lancet 2019 Jun;10191(393):2636-2646

Ranathunga R, Hill T, Mathers J, Francis R, Prentice A, Schoenmakers I, Aspray T. No effect of monthly supplementation with 12000 IU, 24000 IU or 48000 IU vitamin D3 for one year on muscle function: The vitamin D in older people study The Journal of Steroid Biochemistry and Molecular Biology 2019 Jun;0(190):256-262

Lees JS, Chapman FA, Witham MD, Jardine AG, Mark PB. Vitamin K status, supplementation and vascular disease: a systematic review and meta-analysis Heart (British Cardiac Society) 2019 June;12(105):938-945

Donaldson AI, Soiza RL, Hands KJ, Witham MD, Myint PK. Variability in the clinical management of iron deficiency anaemia in older adults: results from a survey of UK specialists in the care of older people Therapeutic Advances in Drug Safety 2019 Jun 13;0(10)

Farre-Garros R, Lee JY, Natanek SA, Connolly M, Sayer AA, Patel H, Cooper C, Polkey MI, Kemp PR. Quadriceps miR-542-3p and -5p are elevated in COPD and reduce function by inhibiting ribosomal and protein synthesis Journal of Applied Physiology 2019 May 31;6(126):1514-1524

Parker SG, Corner L, Laing K, Nestor G, Craig D, Collerton J, Frith J, Roberts HC, Sayer AA, Allan LM, Robinson L, Cowan K, undefined U. Priorities for research in multiple conditions in later life (multi-morbidity): findings from a James Lind Alliance Priority Setting Partnership Age and Ageing 2019 May;3(48):401-406

Hurst C, Scott JPR, Weston KL, Weston M. High-Intensity Interval Training: A Potential Exercise Countermeasure During Human Spaceflight Frontiers in physiology 2019 May 22;0(10):581

Hurst C, Weston KL, Weston M. The effect of 12 weeks of combined upper- and lower-body high-intensity interval training on muscular and cardiorespiratory fitness in older adults Aging clinical and experimental research 2019 May;5(31):661-671

Witham MD, Roberts HC, Gladman J, Stott DJ, Sayer AA, Aspray TJ, Brock P, Clegg A, Cox N, Ewan V, Frith J, Burton JK, Jackson T, Lewis EG, Lim SE, Makin S, Lochlainn MN, Richardson S, Shenkin SD, Steves CJ, Todd O, Tullo E, Walker R, Yarnall A, undefined U. Growing research in geriatric medicine Age and Ageing 2019 May;3(48):316-319

Wylie G, Torrens C, Campbell P, Frost H, Gordon AL, Menz HB, Skelton DA, Sullivan F, Witham MD, Morris J. Podiatry interventions to prevent falls in older people: a systematic review and meta-analysis Age and Ageing 2019 May;3(48):327-336

Garrard JW, Cox NJ, Dodds RM, Roberts HC, Sayer AA. Comprehensive geriatric assessment in primary care: a systematic review Aging clinical and experimental research 2019 Apr 09;0(0):10.1007/s40520-019-01183-w

Marsh R, Salika T, Crozier S, Robinson S, Cooper C, Godfrey K, Inskip H, Baird J, Group USS. The association between crowding within households and behavioural problems in children: Longitudinal data from the Southampton Women's Survey Paediatric and perinatal epidemiology 2019 Apr 29;3(33):195-203

Witham MD. Bridging the gap between the laboratory and the clinic for patients with sarcopenia Biogerontology 2019 Apr;2(20):241-248

Taylor RS, Walker S, Smart NA, Piepoli MF, Warren FC, Ciani O, Whellan D, O’Connor C, Keteyian SJ, Coats A, Davos CH, Dalal HM, Dracup K, Evangelista LS, Jolly K, Myers J, Nilsson BB, Passino C, Witham MD, Yeh GY. Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure Journal of the American College of Cardiology 2019 Apr;12(73):1430-1443

Dismore LL, Echevarria C, Wersch AV, Gibson J, Bourke S. What are the positive drivers and potential barriers to implementation of hospital at home selected by low-risk DECAF score in the UK: a qualitative study embedded within a randomised controlled trial BMJ open 2019 Apr 4;4(9):e026609

Dodds RM, Pakpahan E, Granic A, Davies K, Sayer AA. The recent secular trend in grip strength among older adults: findings from the English Longitudinal Study of Ageing European Geriatric Medicine 2019 Mar 6;3(10):395-401

Lim S, Ibrahim K, Dodds R, Purkis A, Baxter M, Rogers A, Sayer AA, Roberts HC. Physical activity in hospitalised older people: the feasibility and acceptability of a volunteer-led mobility intervention in the SoMoVe™ study Age and Ageing 2019 Mar;0(0):afz114

(Jzh) JH, (Jyh) JH, Warthon-Medina M, Hancock N, Greathead K, Knowles B, Vargas-Garcia E, Gibson LE, Bush LA, Margetts B, Robinson S, Ness A, Alwan NA, Wark PA, Roe M, Finglas P, Steer T, Page P, Johnson L, Roberts K, Amoutzopoulos B, Burley VJ, Greenwood DC, Cade JE. A systematic review of reviews identifying UK validated dietary assessment tools for inclusion on an interactive guided website for researchers: www.nutritools.org Critical Reviews in Food Science and Nutrition 2019 Mar 18;0(0):1-25

Thake M, Stott DJ, Witham MD. Clinical research methods for studies of older people Age and ageing 2019 Mar;2(48):169-170

Granic A, Sayer A, Robinson S. Dietary Patterns, Skeletal Muscle Health, and Sarcopenia in Older Adults Nutrients 2019 Mar 30;4(11):745

Aspray TJ, Hill TR. Osteoporosis and the Ageing Skeleton Sub-cellular biochemistry 2019 Mar 20;0(91):453-476

Hu MK, Witham MD, Soiza RL. Oral Bicarbonate Therapy in Non-Haemodialysis Dependent Chronic Kidney Disease Patients: A Systematic Review and Meta-Analysis of Randomised Controlled Trials Journal of clinical medicine 2019 Feb 7;2(8):208

Ibrahim K, Howson FFA, Culliford DJ, Sayer AA, Roberts HC. The feasibility of assessing frailty and sarcopenia in hospitalised older people: a comparison of commonly used tools BMC Geriatrics 2019 Feb 15;1(19):42

Hesketh KR, Brage S, Cooper C, Godfrey KM, Harvey NC, Inskip HM, Robinson SM, Sluijs EMFV. The association between maternal-child physical activity levels at the transition to formal schooling: cross-sectional and prospective data from the Southampton Women's Survey The international journal of behavioral nutrition and physical activity 2019 Feb 20;1(16):23

Witham MD, Stott DJ. A new dawn for sarcopenia Age and ageing 2019 Jan;1(48):2-3

Syddall HE, Simmonds SJ, Carter SA, Robinson SM, Dennison EM, Cooper C, Group UHCSR. The Hertfordshire Cohort Study: an overview F1000Research 2019 Jan;0(8):82

Mendonça N, Granic A, Hill TR, Siervo M, Mathers JC, Kingston A, Jagger C. Protein Intake and Disability Trajectories in Very Old Adults: The Newcastle 85+ Study Journal of the American Geriatrics Society 2019 Jan;1(67):50-56

Mendonça N, Jagger C, Granic A, Martin-Ruiz C, Mathers JC, Seal CJ, Hill TR. Plasma Vitamin B12, Supplementation and Mortality The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Jan;1(74):138

Lee LV, Crozier SR, Aris IM, Tint MT, Sadananthan SA, Michael N, Quah PL, Robinson SM, Inskip HM, Harvey NC, Barker M, Cooper C, Velan SS, Lee YS, Fortier MV, Yap F, Gluckman PD, Tan KH, Shek LP, Chong Y, Godfrey KM, Chong MFF. Prospective associations of maternal choline status with offspring body composition in the first 5 years of life in two large mother–offspring cohorts: the Southampton Women’s Survey cohort and the Growing Up in Singapore Towards healthy Outcomes cohort International Journal of Epidemiology 2019 Jan;2(48):433-444

Howel D, Moffatt S, Haighton C, Bryant A, Becker F, Steer M, Lawson S, Aspray T, Milne EMG, Vale L, McColl E, White M. Does domiciliary welfare rights advice improve health-related quality of life in independent-living, socio-economically disadvantaged people aged ≥60 years? Randomised controlled trial, economic and process evaluations in the North East of England PloS one 2019 Jan 10;1(14):e0209560

Hurst C, Weston KL, McLaren SJ, Weston M. The effects of same-session combined exercise training on cardiorespiratory and functional fitness in older adults: a systematic review and meta-analysis Aging clinical and experimental research 2019 Jan 19;12(31):1701-1717

Haighton C, Moffatt S, Howel D, Steer M, Becker F, Bryant A, Lawson S, McColl E, Vale L, Milne E, Aspray T, White M. Randomised controlled trial with economic and process evaluations of domiciliary welfare rights advice for socioeconomically disadvantaged older people recruited via primary health care (the Do-Well study) Public Health Research 2019 Jan;3(7)

Harling G, Payne CF, Davies JI, Gomez-Olive FX, Kahn K, Manderson L, Mateen FJ, Tollman SM, Witham MD. Impairment in Activities of Daily Living, Care Receipt, and Unmet Needs in a Middle-Aged and Older Rural South African Population: Findings From the HAALSI Study Journal of Aging and Health 2019 Jan 2;0(0):089826431882122

Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM, Sieber CC, Topinkova E, Vandewoude M, Visser M, Zamboni M, (EWGSOP2) UWGFTEWGOSIOP2, EWGSOP2 ATEGF. Sarcopenia: revised European consensus on definition and diagnosis Age and ageing 2019 Jan ;1(48):16-31

Aspray TJ, Chadwick T, Francis RM, McColl E, Stamp E, Prentice A, Wilamowitz-Moellendorff AV, Schoenmakers I. Randomized controlled trial of vitamin D supplementation in older people to optimize bone health The American journal of clinical nutrition 2019 Jan;1(109):207-217

Cox N, Ibrahim K, Sayer A, Robinson S, Roberts H. Assessment and Treatment of the Anorexia of Aging: A Systematic Review Nutrients 2019 Jan 11;1(11):144